C1QTNF5

C1QTNF5
Uygun yapılar
PDB	Ortolog araması: PDBe RCSB
PDB kimlik kodlarının listesi
	4F3J, 4NN0
Tanımlayıcılar
Başka adlar	C1QTNF5
Dış kimlikler	OMIM: 608752 MGI: 2385958 HomoloGene: 9227 GeneCards: C1QTNF5
Gen yerleşimi (İnsan)
Krom.	11. Kromozom (insan)
Bitiş	119,340,940 bç
Gen ontolojisi
Moleküler işlevi	• identical protein binding;
Hücresel bileşeni	• extracellular region; • Kollajen; • cell projection; • membrane; • lateral plasma membrane; • apical plasma membrane; • Hücre zarı; • transport vesicle; • bicellular tight junction; • extracellular space;
Biyolojik süreci	• protein secretion; • protein trimerization; • inner ear development;
	Kaynaklar:Amigo / QuickGO
Ortologlar
	114902
	235312
	ENSG00000223953
	ENSMUSG00000079592
	Q9BXJ0
	Q8K480; Q8K479
	NM_015645; NM_001278431
	NM_001040631; NM_001040632; NM_001190313; NM_001190319; NM_145613
	NP_001265360; NP_056460
NP_001177243; NP_667337; NP_001035721; NP_001035722; NP_001177242;
	NP_001177248; NP_663588
	Vikiveri
İnsan'ı Gör/Düzenle	Fare'yi Gör/Düzenle

C1q/tümör nekroz faktör ilişkili protein 5, insanların 11. kromozomunda yer alan C1QTNF5 geni tarafından kodlanan bir proteindir.^[4]^[5]

Kaynakça değiştir

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000223953 - Ensembl, May 2017
^ "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lando, Leonardo; Borooah, Shyamanga (30 Eylül 2022). "Late-Onset Retinal Degeneration: Clinical Perspectives". Clinical Ophthalmology (İngilizce). Cilt 16. ss. 3225-3246. doi:10.2147/OPTH.S362691. PMC 9531619 $2. PMID 36204011.
^ "Entrez Gene: C1QTNF5 C1q and tumor necrosis factor related protein 5". 2 Kasım 2008 tarihinde kaynağından arşivlendi.

Ek okuma değiştir

Shapiro L, Scherer PE (March 1998). "The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor". Current Biology. 8 (6). ss. 335-8. doi:10.1016/S0960-9822(98)70133-2. PMID 9512423.
Hayward C, Shu X, Cideciyan AV, Lennon A, Barran P, Zareparsi S, Sawyer L, Hendry G, Dhillon B, Milam AH, Luthert PJ, Swaroop A, Hastie ND, Jacobson SG, Wright AF (October 2003). "Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration". Human Molecular Genetics. 12 (20). ss. 2657-67. doi:10.1093/hmg/ddg289. PMID 12944416.
Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10). ss. 2819-24. doi:10.1110/ps.04682504. PMC 2286551 $2. PMID 15340161.
Ayyagari R, Mandal MN, Karoukis AJ, Chen L, McLaren NC, Lichter M, Wong DT, Hitchcock PF, Caruso RC, Moroi SE, Maumenee IH, Sieving PA (September 2005). "Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation". Investigative Ophthalmology & Visual Science. 46 (9). ss. 3363-71. doi:10.1167/iovs.05-0159. PMID 16123441.
Subrayan V, Morris B, Armbrecht AM, Wright AF, Dhillon B (December 2005). "Long anterior lens zonules in late-onset retinal degeneration (L-ORD)". American Journal of Ophthalmology. 140 (6). ss. 1127-9. doi:10.1016/j.ajo.2005.06.023. PMID 16376663.
Foster LJ, Rudich A, Talior I, Patel N, Huang X, Furtado LM, Bilan PJ, Mann M, Klip A (January 2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". Journal of Proteome Research. 5 (1). ss. 64-75. doi:10.1021/pr0502626. PMID 16396496.
Shu X, Tulloch B, Lennon A, Vlachantoni D, Zhou X, Hayward C, Wright AF (May 2006). "Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5". Human Molecular Genetics. 15 (10). ss. 1680-9. doi:10.1093/hmg/ddl091. PMID 16600989.
Shu X, Tulloch B, Lennon A, Hayward C, O'Connell M, Cideciyan AV, Jacobson SG, Wright AF (2007). "Biochemical Characterisation of the C1QTNF5 Gene Associated with Late-Onset Retinal Degeneration". Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology. 572. ss. 41-8. doi:10.1007/0-387-32442-9_7. ISBN 978-0-387-28464-4. PMID 17249553.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000223953 - Ensembl, May 2017

[2] "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Lando_3225–3246-4] Lando, Leonardo; Borooah, Shyamanga (30 Eylül 2022). "Late-Onset Retinal Degeneration: Clinical Perspectives". Clinical Ophthalmology (İngilizce). Cilt 16. ss. 3225-3246. doi:10.2147/OPTH.S362691. PMC 9531619 $2. PMID 36204011.

[entrez-5] "Entrez Gene: C1QTNF5 C1q and tumor necrosis factor related protein 5". 2 Kasım 2008 tarihinde kaynağından arşivlendi.

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