ALDH3B1

ALDH3B1
Tanımlayıcılar
Başka adlar	ALDH3B1
Dış kimlikler	OMIM: 600466 MGI: 1914939 HomoloGene: 73890 GeneCards: ALDH3B1
Gen yerleşimi (İnsan)
Krom.	11. Kromozom (insan)
Bitiş	68,029,282 bç
Gen ontolojisi
Moleküler işlevi	• 3-chloroallyl aldehyde dehydrogenase activity; • GO:0001948, GO:0016582 protein bağlanması; • oxidoreductase activity; • aldehyde dehydrogenase [NAD(P)+ activity]; • aldehyde dehydrogenase (NAD+) activity; • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;
Hücresel bileşeni	• Vezikül; • membrane; • Hücre zarı; • extracellular exosome; • secretory granule membrane; • specific granule membrane; • sitoplazma; • Sitozol;
Biyolojik süreci	• ethanol catabolic process; • lipid metabolism; • aldehyde catabolic process; • sphingolipid biosynthetic process; • cellular aldehyde metabolic process; • cellular response to oxidative stress; • Metabolizma; • alcohol metabolic process; • neutrophil degranulation;
	Kaynaklar:Amigo / QuickGO
Ortologlar
	221
	67689
	ENSG00000006534
	ENSMUSG00000024885
	P43353; Q9BUJ8
	Q80VQ0
	NM_001290059; NM_000694; NM_001030010; NM_001161473; NM_001290058
	NM_026316
	NP_000685; NP_001025181; NP_001154945; NP_001276987; NP_001276988
	NP_080592
	Vikiveri
İnsan'ı Gör/Düzenle	Fare'yi Gör/Düzenle

Aldehit dehidrogenaz aile 3, üye B1, insanların 11. kromozomunda yer alan ALDH3B1 geni tarafından kodlanan bir enzimdir.^[4]^[5]

Kaynakça değiştir

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000006534 - Ensembl, May 2017
^ "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family". Gene. 151 (1–2). ss. 285-9. doi:10.1016/0378-1119(94)90672-6. PMID 7828891.
^ Hsu LC, Chang WC, Yoshida A (Apr 1997). "Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison". Gene. 189 (1). ss. 89-94. doi:10.1016/S0378-1119(96)00839-6. PMID 9161417.

Further reading değiştir

Sun X, Jia Y, Zhang X, Xu Q, Shen Y, Li Y (Jun 2005). "Multi-locus association study of schizophrenia susceptibility genes with a posterior probability method". Science in China Series C: Life Sciences. 48 (3). ss. 263-9. doi:10.1007/bf03183620. PMID 16092759.
Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family". Gene. 151 (1–2). ss. 285-9. doi:10.1016/0378-1119(94)90672-6. PMID 7828891.
Marchitti SA, Orlicky DJ, Vasiliou V (May 2007). "Expression and initial characterization of human ALDH3B1". Biochemical and Biophysical Research Communications. 356 (3). ss. 792-8. doi:10.1016/j.bbrc.2007.03.046. PMC 1899873 $2. PMID 17382292.
Saito A, Kawamoto M, Kamatani N (Jun 2009). "Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects". Journal of Human Genetics. 54 (6). ss. 317-23. doi:10.1038/jhg.2009.31. PMID 19343046.
Wang Y, Hu Y, Fang Y, Zhang K, Yang H, Ma J, Xu Q, Shen Y (Jun 2009). "Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia". Biological Psychiatry. 65 (12). ss. 1048-54. doi:10.1016/j.biopsych.2008.11.027. PMID 19159868.
Yoshida A, Rzhetsky A, Hsu LC, Chang C (Feb 1998). "Human aldehyde dehydrogenase gene family". European Journal of Biochemistry. 251 (3). ss. 549-57. doi:10.1046/j.1432-1327.1998.2510549.x. PMID 9490025.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000006534 - Ensembl, May 2017

[2] "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7828891-4] Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family". Gene. 151 (1–2). ss. 285-9. doi:10.1016/0378-1119(94)90672-6. PMID 7828891.

[pmid9161417-5] Hsu LC, Chang WC, Yoshida A (Apr 1997). "Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison". Gene. 189 (1). ss. 89-94. doi:10.1016/S0378-1119(96)00839-6. PMID 9161417.

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