1261 yılında [[Konstantinopolis]]'in geri alınmasından sonra unvan donanmanın başkomutanı olan eski haline getirilmiştir ve imparatorluğun kalanı için ''[[protovestiarios|prōtovestiarios]]'' ile ''[[protostrator|prōtostratōr]]'' arasında yüksek bir derece olarak kalmıştır.{{sfn|ODB|loc="Megas doux", p. 1330}}{{sfn|Bartusis|1997|p=381}}
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After the Byzantine recovery of Constantinople in 1261, the title reverted to its old function as commander-in-chief of the navy, and remained a high rank for the remainder of the empire, its holder ranking sixth after the emperor, between the ''[[protovestiarios|prōtovestiarios]]'' and the ''[[protostrator|prōtostratōr]]''.{{sfn|ODB|loc="Megas doux", p. 1330}}<ref>Bartusis (1997), p. 381</ref> As such, it was also sometimes conferred upon foreigners in imperial service, the most notable among these being the Italian [[Licario]], who recovered many Aegean islands for Emperor Michael VIII,<ref>Bartusis (1997), p. 60</ref> and [[Roger de Flor]], head of the [[Catalan Company]].{{sfn|ODB|loc="Megas doux", p. 1330}} After the mid-14th century, the office was sometimes held together with the office of ''[[mesazon|mesazōn]]'', the chief of the [[Byzantine aristocracy and bureaucracy|imperial secretariat]]. In this capacity, [[Alexios Apokaukos]] served as one of the leading members of the imperial government during the [[Byzantine civil war of 1341-1347|Civil War of 1341-1347]], supporting [[John V Palaiologos]] (r. 1341-1391) against [[John VI Kantakouzenos]] (r. 1347-1354). The last and perhaps most famous ''megas doux'' and ''mesazōn'' was [[Loukas Notaras]], who served under [[Constantine XI Palaiologos]] (r. 1449-1453) until the [[Fall of Constantinople]].
